DEEPDʘSE

Technology

AI precision dosing,clinically bounded.

Deepdose turns passive circadian data into structured timing windows — versioned engines, explicit uncertainty, and a validation ladder your CMO can audit.

The stack

Phase anchor → BTI windows → clinician triage

Pull-sync wearables and questionnaires on dashboard load. Fuse a proxy DLMO, shift medication windows, surface drift — upgrade to TipTraQ when clinical grade matters.

Platform

Four layers, one decision-support loop

Modular services — algorithmic math never mixed with UI controllers.

  • Ingest

    Authorised device pull-sync

    Oura, Whoop, Apple HealthKit, MCTQ, and TipTraQ — triggered on dashboard load, not continuous streaming.

  • Phase

    DLMO fusion ladder

    Proxy DLMO from published behavioural markers; three-tier resolution elevates TipTraQ clinical blocks when present.

  • Compute

    Isolated BTI engine

    Biological Time Index, CHI, and dosing windows — structured JSON payloads only. Evidence-graded phase offsets, not opaque ML scores.

  • Govern

    Chronobiobank isolation

    Model weights and demographic baselines stay server-side. UI receives timing outputs; telemetry is anonymised.

Validation

Estimate first. Prove when it counts.

Every patient starts free; clinical grade is an upgrade path, not a gate.

  1. L3 · Free

    Smartphone proxy

    Sleep onset − 2 h fused with MCTQ mid-sleep − 2.5 h. Confidence capped at 0.55.

    Proxy DLMO methodology →
  2. L2 · Panel

    Blood-panel phase

    Optional melatonin or metabolite panels when ordered — resolves above proxy when confidence threshold met.

  3. L1 · Clinical

    TipTraQ three nights

    Home sleep staging, SpO₂, and respiratory events replace the proxy. Verified clinical-grade badge on record.

    Home test overview →

Clinical boundary

What we are — and what we are not

Decision support

Timing recommendations you approve

Clinicians prescribe; patients accept in-app. BTI surfaces window open, closed, or critical drift — never autonomous dose changes.

Not a prescriber

No diagnosis. No PK modelling.

Not a MedTech accelerator or autonomous prescriber. Windows are phase-adjusted from published chronotherapy offsets — not drug-specific PK/PD simulation.

AI transparency

Rules you can read. Learning you can govern.

Rules-first

Versioned, auditable engines

DLMO proxy (dlmo-proxy-v1), CHI v1, and BTI payloads ship as documented formulas — inspectable, not a black box.

Federated edge

Patterns, not patient warehouses

Chronobiobank ingests anonymised telemetry — consent-gated, pseudonymised. Population models improve without centralising raw nights.

CMO workflow

Built for triage, not another portal

Device gaps and drift rise to the top — validated records earn the clinical badge.

  1. Queue

    Drift & device alerts first

    36-hour sync rule flags empty tokens and stale telemetry. BTI misalignment prioritises the panel.

  2. Validate

    TipTraQ when grade matters

    Three-night home kits set a clinical baseline — sleep staging replaces the proxy anchor.

  3. Retime

    Evidence-graded windows

    Medication-specific offsets shifted by phase. Clinician approves; patient sees plain-language take-now cues.

  4. Audit

    Consent & access trail

    Dynamic consent per purpose — care, research, analytics. Withdraw any time; RLS on every patient row.

Outputs

Structured payloads only

Every dashboard metric maps to a defined schema — suitable for integration and diligence.

  • BTI

    Biological Time Index

    Window open · closed · critical drift — plus clock-relative biological time and dosing window ISO timestamps.

  • CHI

    Circadian Health Index

    0–100 composite: phase offset, social jet lag, vitamin D band, and signal quality — capped when data are stale.

  • BCA

    Body clock alignment

    Melatonin readiness vs lights-out habit — triage hint for adherence drift, not a diagnosis.

  • Windows

    Phase-shifted dosing

    Per-medication windows adjusted by DLMO phase offset — evidence-graded where literature supports timing.

Due diligence

What investors and CMOs ask first

  • Versioned

    Engines ship with explicit version tags in every payload.

  • Isolated

    BTI math decoupled from UI — Chronobiobank weights never in patient UI.

  • 36 h

    Device interruption rule auto-flags stale sync for triage queue.

  • Verified

    Premium tier renders clinical-grade badge on validated TipTraQ records.

  • GDPR

    UK GDPR and HIPAA-shaped workflows — dynamic consent, minimum necessary.

  • Pilot

    Endpoints: in-window dosing, drift, triage time, TipTraQ completion.

Methodology

Go deeper